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Significant Shareholders

Significant Shareholder # Shares Held % Holding
City of London Investment Management Limited 18,566,332 28.44
Baillie Gifford & Co 11,185,600 17.13
Tiberius Investments & Capital (Jersey) Limited 7,187,845 11.01
QVT Financial LP 6,425,000 9.84
FIL Limited 3,607,900 5.53
Glenmede Trust Company/PCT Partners LLC 2,250,000 3.45

The information in the above table was correct as at 12 August 2011.

The transfers of ordinary shares held in certificated form by US persons are subject to the Company’s consent. There are no restrictions on the transfer of shares other than as specified in the Admission Document.